Overview

Amoxicillin is an analog of ampicillin, derived from the basic penicillin nucleus, 6-aminopenicillanic acid. Clavulanic acid is produced by the fermentation of Streptomyces clavuligerus. It is a beta-lactam structurally related to the penicillins and possesses the ability to inactivate some beta-lactamases by blocking the active sites of these enzymes.

What is Zemoxtif-Cl and What it is Used For?

ZEMOXTIF-CL is an antibiotic and works by killing bacteria that cause infections. It contains two different medicines called amoxicillin and clavulanic acid. Amoxicillin belongs to a group of medicines called "penicillins" that can sometimes be stopped from working (made inactive). The other active component (clavulanic acid) stops this from happening.
ZEMOXTIF-CL is used in adults and children to treat the following infections:
•Middle ear and sinus infections
•Respiratory tract infections
•Urinary tract infections
•Skin and soft tissue infections including dental infections
•Bone and joint infections.

Why is this medication prescribed?

The combination of amoxicillin and clavulanic acid is used to treat certain infections caused by bacteria, including infections of the ears, lungs, sinus, skin, and urinary tract. Amoxicillin is in a class of medications called penicillin-like antibiotics. It works by stopping the growth of bacteria. Clavulanic acid is in a class of medications called beta-lactamase inhibitors. It works by preventing bacteria from destroying amoxicillin. Antibiotics will not work for colds, flu, or other viral infections.

Other uses for this medicine

Amoxicillin and clavulanic acid also is used sometimes to treat certain sexually transmitted diseases (STD). Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Warnings

Do not take ZEMOXTIF-CL:

If you are allergic (hypersensitive) to amoxicillin, clavulanic acid, penicillins or any of the other ingredients of ZEMOXTIF-CL tablets.

If you have ever had a severe allergic (hypersensitive) reaction to any other antibiotic. This can include a skin rash or swelling of the face or neck.

If you have ever had liver problems or jaundice (yellowing of the skin) when taking an antibiotic.

Do not take ZEMOXTIF-CL if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking ZEMOXTIF-CL.

Contraindications

Amoxicillin + Clavulanic Acid and Pregnancy

Category B:Either animal-reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1st trimester (and there is no evidence of a risk in later trimesters).

Amoxicillin + Clavulanic Acid and Lactation

Caution when used during lactation
Ampicillin-class antibiotics are excreted in human milk; therefore, caution should be exercised when Amoxicillin and Clavulanic acid is administered to a nursing woman.

Amoxicillin + Clavulanic Acid and Children

Safety and efficacy of Amoxicillin and Clavulanic acid for Oral Suspension 600 mg/42.9 mg per 5 mL in infants younger than 3 months have not been established. Safety and efficacy of Amoxicillin and Clavulanic acid for Oral Suspension 600 mg/42.9 mg per 5 mL have been demonstrated for treatment of acute otitis media in infants and children 3 months to 12 years

Amoxicillin + Clavulanic Acid and Other Contraindications

Penicillin allergy

Side Effects

Zemoxtif-Cl ( Amoxicillin and Clavulanic Acid) may cause side effects.

Diarrhea

Upset stomach

Vomiting

Mild skin rash

Dosage

Oral

This is Preferred Dosage:
Adult: Based on amoxicillin dose, 250-500 mg every 8 hours or 500-750 mg every 12 hours.
Child: Based on amoxicillin dose: 125-250 mg every 8 hours.
Children weighing <40 kg: 20-40 mg/kg/day in divided doses every 8 hours.
Infants <3 months: up to 30 mg/kg/day in divided doses every 12 hours.

Disclaimer:To be taken only after consulting with the doctor.

Storage

Keep your medicine in its original packaging until it is time to take it. If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25 degrees C. Protect it from moisture.